Abstract
Patients undergoing thoracotomy reportedly have up to 75% risk of developing chronic post-operative pain secondary to this life-saving surgery. Multiple factors have been implicated for increased risk of worse post-operative pain (POP) trajectory including baseline pain sensitivity, pre-existing conditions, negative affect and maladaptive coping. Additionally, sleep disruptions are common and quite significant among post-operative patients, but only recently have investigators considered multiple facets of sleep, pain and genetic susceptibility to dysfunction in both as potentially contributing risks for increased post-surgical acute and chronic pain.
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