Abstract

Purpose: Accelerated knee osteoarthritis (KOA) is characterized by more pain, impaired physical function, and greater likelihood to receive a joint replacement compared to individuals who develop the typical gradual onset of disease. Prognostic tools are needed to provide earlier discrimination between individuals that develop accelerated KOA compared to people that go on to develop typical KOA. Prior to disease onset, people with accelerated KOA are more likely to present with cruciate ligament degeneration compared to those that develop typical KOA.

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