Abstract

A new series of β-type biomedical alloys Ti50Zr25Nb20Cu5−xAgx (x = 0, 1 and 2.5 at%) have been developed. Mechanical properties, antibacterial properties, and biocompatibility of the alloys were systematically investigated. These alloys are body-centered cubic (BCC) phase solid solution with dendritic structure and excellent yield strength and hardness. Meanwhile, the alloys exhibit low Young’s modulus (~61 GPa) which is only half of the Ti-6Al-4 V alloy and close to the level of human bone modulus. Due to the increases of the total content of Cu2+ and Ag+ ions with the Ag partial substitution of Cu, the antibacterial properties of the alloys improves significantly and the antibacterial rate of Ti50Zr25Nb20Cu2.5Ag2.5 alloy is above 99.6%. In vitro experiments demonstrate the biocompatibility of Ti50Zr25Nb20Cu2.5Ag2.5 alloy is comparable to Ti-6Al-4 V alloy. These β-type Ti50Zr25Nb20Cu5−xAgx (x = 0, 1 and 2.5 at%) alloys with superior material mechanical properties, excellent antibacterial properties and good biocompatibility have great potential for antibacterial biomedical implants and associated materials.

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