Abstract
Atrial fibrillation (AF) is the most sustained cardiac arrhythmia requiring medical care. Amiodarone is a di-iodinated benzofuran derivative widely used for preventing the recurrences of AF [1]. Although amiodarone is the most effective agent in rhythm control of AF [2], the adverse effects of amiodarone frequently result in treatment discontinuations. Hypothyroidism caused by the iodine in amiodarone is one of the most frequent and important adverse effects. The incidence of amiodarone-induced hypothyroidism varies from 1 to 32% [3–7].
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