Abstract
Immediately after birth thyrotropin (TSH) levels in plasma are higher in newborns than in adults (1). 48 hours later the elevated TSH levels decline by two thirds. From the 3rd day on they gradually reach adult levels. In three newborns with congenital goiter due to high iodine intake by their mothers during pregnancy, Job et al. (2) found excessively high TSH levels in plasma. This prompted us to investigate plasma TSH, PBI, TBI, total T4 and bone age in 23 newborns with congenital goiter. 43 normal newborns served as controls in order to establish normal ranges. Plasma TSH was determined by the double antibody radioimmunoassay according to Odell et al. (3).
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