Abstract
ABSTRACT Objective: The objective of this study was to present a case series of thyrotoxic periodic paralysis (TPP) in 8 males of Hispanic origin diagnosed at 1 hospital. Methods: This report summarizes the clinical presentations, laboratory values, treatments, and follow-up for a series of patients with TPP. The diagnosis of thyrotoxicosis was based on clinical features and laboratory criteria. The TPP diagnostic criteria were acute muscle weakness, thyrotoxic symptoms, and hypokalemia. Results: All 8 study patients with TPP were Hispanic males ranging in age from 25 to 36 years (mean ± SD, 31 ± 4.4 years). Six patients presented with upper and lower extremity weakness, while 2 patients had only lower extremity weakness. All TPP episodes occurred at night and in the early morning. TPP-associated weakness resolved within 24 hours, either spontaneously or following therapy with potassium chloride (40 to 120 mEq), beta blockers, and methimazole. Six patients had a history of at least 1 previous TPP episode....
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