Abstract

Thyrotoxic Periodic Paralysis (TPP) is a rare diagnosis in the western world; however, its incidence has been rising in recent years due to globalization. This condition has the potential to be deadly if not detected and treated in a time appropriate manner. This case discusses our management of a patient who came into our hospital with complaints of total body numbness and weakness for several hours. He was subsequently diagnosed with TPP and was treated with Methimazole and aggressive potassium supplementation and had an overall good outcome. This case report highlights an unusual disease that needs to be considered as a differential when a young man reports numbness and weakness to the clinician.

Highlights

  • Thyrotoxic Periodic Paralysis (TPP) is a rare diagnosis in the western world; its incidence has been rising in recent years due to globalization

  • Thyrotoxic periodic paralysis (TPP) is a disease categorized as weakness and paralysis due to hypokalemia in the setting of hyperthyroidism

  • Thyrotoxic Periodic Paralysis is a rare disease that was first documented by Dr Rosenfeld back in 1902

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Summary

Introduction

Thyrotoxic periodic paralysis (TPP) is a disease categorized as weakness and paralysis due to hypokalemia in the setting of hyperthyroidism. Thyrotoxic Periodic Paralysis (TPP) is a rare diagnosis in the western world; its incidence has been rising in recent years due to globalization. He was subsequently diagnosed with TPP and was treated with Methimazole and aggressive potassium supplementation and had an overall good outcome. TPP is rarely seen in North America, with an incidence of 1/100,000 [1], and it affects only 1%-2% of thyrotoxic patients in the United States.

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