Thyroid Storm-induced Takotsubo Cardiomyopathy Presenting as Acute Chest Pain: A Case Report.

Brayden Ashdown,Emilie Hynes

doi:10.5811/cpcem.2021.4.52005

Abstract

IntroductionStress-induced cardiomyopathy is a rare but serious cause of chest pain, which in recent studies has been shown to carry a similar in-hospital mortality to acute ST-elevation myocardial infarction. The pathophysiology of the disease is thought to be secondary to dysregulated catecholamine effects on myocardium.Case ReportWe present a case of a previously healthy female without known thyroid disease who presented to the emergency department for acute chest pain and was found to have thyroid storm-induced cardiomyopathy in a typical stress-induced cardiomyopathy pattern without evidence of coronary disease on catheterization.ConclusionThyrotoxicosis can cause dysregulation of catecholamines and is a rare cause of stress-induced cardiomyopathy. It requires distinct therapies and should be considered by emergency physicians in the workup of acute chest pain with concern for stress-induced cardiomyopathy.

Highlights

Stress-induced cardiomyopathy is a rare but serious cause of chest pain, which in recent studies has been shown to carry a similar in-hospital mortality to acute ST-elevation myocardial infarction
Case Report: We present a case of a previously healthy female without known thyroid disease who presented to the emergency department for acute chest pain and was found to have thyroid storminduced cardiomyopathy in a typical stress-induced cardiomyopathy pattern without evidence of coronary disease on catheterization
More recent studies have demonstrated an early in-hospital mortality of around 4-5%, a figure “comparable to that of ST-segment elevation myocardial infarction [STEMI] in the era of primary percutaneous coronary interventions.”[2]. These findings highlight the importance of early recognition and treatment, as well as a more complete understanding of the underlying pathophysiology

Summary

Introduction

Stress-induced cardiomyopathy is a rare but serious cause of chest pain, which in recent studies has been shown to carry a similar in-hospital mortality to acute ST-elevation myocardial infarction.

Conclusion

INTRODUCTION

DISCUSSION

CONCLUSION