Abstract
Neonatal thyroid secretion rates (TSR) were determined by a direct output method. The neonatal rat has a low level of thyroidal function at birth, and this condition persists until the animal weighs 22 gm. Thereafter, there is an abrupt increase in TSR and the thyroid iodine content, both of which, from that time on, vary linearly with the logarithm of body weight. This relationship is maintained at least until the rats weight 244 gm, at an age of about 60 days. The existence of a mother-infant iodine cycle was confirmed. Approximately 9.36% of the average 131I count in thyroid glands of tagged litter-mates was transferred within 48 hours via the mother's milk to an untagged foster rat of the same age. The number of rats in the litter, their ages, and their weights had no influence on the amount of cycled iodine.
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