Thyroid iodine content and turnover in euthyroid subjects: validity of estimation of thyroid iodine accumulation from short-term clearance studies.

Abstract

Measurements of thyroidal (k1) and renal (k2) radioiodine clearances, urinary iodine excretion (qe) and fractional thyroidal radioiodine release rate (αk) were conducted in 18 euthyroid young adult subjects in presumed iodine equilibrium, enabling the thyroid iodine accumulation (A) to be calculated. Thyroid iodide content (TI) was also calculated as: