Abstract
Introduction Chronic obstructive pulmonary disease (COPD) is one of the most common causes of morbidity and mortality worldwide. The disease is characterized by progressive airway inflammation, which not only affects the airways but also has systemic effects that are associated with comorbidities. Although comorbid conditions such as hypertension and coronary artery disease are very well-known in COPD patients, diseases of the thyroid gland have not been sufficiently studied. Therefore, thyroid diseases are not considered among the comorbid conditions of COPD. The purpose of this study was to determine the thyroid gland disease (TGD) prevalence in COPD and associated factors. Materials and Method. The study included 309 (297 (96%) male) patients. The patients were subjected to spirometry and thyroid function tests (TFT) in the stable period. The thyroid gland disease they were diagnosed with was recorded after face-to-face meetings and examining their files. Results The mean age of the patients who were included in the study was 65.9 ± 9.8 (40-90). Thyroid disease was determined in 68 (22%) individuals. There were hypothyroidism in 7 (2%), euthyroidism in 45 (15%), and hyperthyroidism in 16 (%5) patients. No relationship was found between the severity of airflow limitation and the prevalence of TGD. Conclusion Thyroid abnormalities are commonly observed in COPD. The most frequently encountered TGDs are euthyroid multinodular goiter, euthyroid sick syndrome (ESS), and toxic multinodular goiter.
Highlights
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of morbidity and mortality worldwide
The prevalence of thyroid gland disease (TGD) was found to be as high as 22% among COPD patients with a mean age of 65:9 ± 9:8
The most frequent thyroid gland diseases were those with euthyroidism, followed by hyperthyroidism and hypothyroidism, respectively
Summary
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of morbidity and mortality worldwide. The disease is characterized by progressive airway inflammation, which affects the airways and has systemic effects that are associated with comorbidities Comorbid conditions such as hypertension and coronary artery disease are very well-known in COPD patients, diseases of the thyroid gland have not been sufficiently studied. The purpose of this study was to determine the thyroid gland disease (TGD) prevalence in COPD and associated factors. COPD is accompanied by other diseases that are expressed as comorbidities and significantly affect its prognosis While some of these emerge independently of COPD, some of them are interrelated due to common risk factors such as smoking and advanced age [3]. Depression, skeletal muscle myopathies, and mental disorders are seen as comorbid conditions [6]
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