Abstract
Objective To investigate changes of thyroid functions in high-risk pregnant women suffering from gestational diabetes mellitus(GDM). Methods From Feb. 2013 to Jun. 2014, 80 cases of high-risk pregnant women suffering from GDM were selected as group A1(high-risk group), 80 cases of GDM pregnant women were selected as group A2(diabetic group), and 80 cases of healthy pregnant women were selected as group A3(the control group). Indicators of thyroid function for the three groups were detected and compared. Results The positive rate of TPOAb in group A1 and A2 was significantly higher than that in group A3, and the difference had statistical significance(P 0.05), while FT4 level in group A1 and A2 was both significantly lower than that in group A3, and the difference had statistical significance(P<0.05). Conclusions The probability of thyroid dysfunction in GDM pregnant women and high-risk pregnant women is higher than that in the normal healthy pregnant women. For pregnant women with a family history of diabetes, thyroid functions should be checked comprehensively to prevent thyroid dysfunction. Key words: Gestational diabetes; High-risk pregnant women; Thyroid function; Thyroid autoantibodies
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