THYROID FUNCTION ABNORMALITIES IN COVID-19 PATIENTS.

Abstract

COVID-19 has a great physical and psychological impact on each group of society, including the deterioration in physical health, unapproachable health care facilities, psychological upset, stress, anxiety, depression, etc. The initiated immune response by COVID-19 leads to overt thyroid dysfunction by interfering the desiodases and thyroid transport proteins. The T3 level is inversely proportional to IL-6 with a modest decrease of TSH and T4. This cross - sectional, observational study was aimed to evaluate the thyroid prole abnormalities in patients with COVID-19 pneumonia and to nd out its relation to the severity of disease. Atotal of 100 COVID-19 patients were involved in the study. Adetailed history was collected. Thyroid function test, including TSH, TT3 and TT4, Procalcitonin and IL-6 were done for all the patients. The majority (36%) of the patients were in the age group of 48 to 57 years of age and male female ratio in COVID-19 group was 1.17:1. A signicant correlation was found between thyroid alteration with severity of disease. It was concluded that among patients diagnosed with COVID-19 had signicant thyroid alterations