Abstract
To the Editor.— In the editorial on thyroid dysfunction, Nusynowitz and Young (242:275, 1979) speculated on the possible usefulness of serum reverse triiodothyronine (T 3 ) levels in differentiating sick patients with isolated hyperthyroxinemia (low or normal serum T 3 values) from sick patients with hyperthyroidism. We measured serum reverse T 3 concentrations in the group of sick patients described in the same issue ofThe Journal(242:251, 1979). 1 The mean serum reverse T 3 concentration was significantly higher in the study group, at 65±20 ng/dL, vs 24±5 ng/dL ( P 3 means (61±20 ng/dL and 43±7 ng/dL, respectively). Thus, serum reverse T 3 values seem to be of no value in distinguishing sick euthyroid patients with high serum free thyroxine indices from sick hyperthyroid patients.
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