Thyroid Disease

Abstract

Part 1 Historical introduction: thyroidology - reflections on 20th century history. Part 2 Basic clinical sciences: surgical anatomy and embryology of the lower neck and superior mediastinum physiology of thyroid hormone synthesis, secretion and transport clinical approach to thyroid function testing parathyroid function and calcium homeostasis pathology of thyroid disease fine needle biopsy of the thyroid uptake tests, thyroid and whole body imaging with isotopes diagnostic imaging of the thyroid gland. Part 3 Molecuar biology of the thyroid gland: molecular basis of thyroid disease molecular biology of the TSH receptor thyroid hormone resistance syndromes oncogenes and thyroid cancer. Part 4 Hyperthyroidism: hyperthyroidism - systematic effects and differential diagnosis medical management of hyperthyroidism - theoretical and practical aspects treatment of hyperthyroidism with 131-I surgical treatment of hyperthyroidism thyroid-associated ophthalmology - aetiology and pathogenesis thyroid associated ophthalmology - treatment. Part 5 Hypothyroidism: clinical manifestations and differential diagnosis of hypothyroidism. Part 6 Thyroiditis - nodular and congenital thyroid disease: thyroiditis solitary thyroid nodule - concepts in diagnosis and treatment multinodular goiter management of substernal thyroid disease management of thyroid disorders involving the airway congential thyroid cysts and ectopic thyroid. Part 7 Treatment with thyroid hormone: replacement and suppressive treatment with thyroid hormone. Part 8 Thyroid cancer: thyroid cancer - controversies and aetiopathogenesis evaluation and surgical treatment of papillary and follicular carcinoma thyroglobulin in benign and malignant thyroid disease 131-I and external radiation in the treatment of local metastic thyroid cancer medullary and thyroid carcinoma and the multiple endocrine neoplasia syndromes anaplastic carcinoma, lymphona and the unusual malignancies, and chemotherapy for thyroid cancer management of thyroid carcinoma invading the upper aerodigestive system. Part 9 Surgery of the thyroid gland: general and regional anaesthesia for thyroid surgery the technique of thyroidectomy by cervical and thoracic approaches complications of thyroid surgery - an overview nonmetabolic complications of thyroid surgery metabolic complications of thyroid surgery metabolic complications of thyroid surgery - thyrotoxic storm.