Abstract
Considering the rising incidence of thyroid cancer worldwide, the aim of our study was to investigate the temporal trends in the incidence of this cancer in a large population of Iranian patients. We used the Iran Cancer Data System (ICDS) Registry to assess the thyroid cancer trend from 2004 to 2010 with regard to different genders, age groups, and morphologies. To do this we analyzed the data of 10,913 new cases of thyroid cancer that occurred during these years. The incidence rate (per one year) of thyroid cancer was 2.20 per 100,000 persons between 2004 and 2010 in Iran. Papillary thyroid cancer was the most common histology type, with an annual rate of 0.29 in Iran. The highest rate of prevalence in thyroid cancer was observed at the age of 45 years at the time of diagnosis. We found a female-to-male ratio of 2 in Iran. A significant decrease was detected in the trend of thyroid cancer in children <19y, which was not correlated to the trend of older patients. As expected, the trend of thyroid cancer increased over the 7 years, primarily contributed by papillary thyroid cancer. A rising pattern of incidence was seen in all the age groups except patients aged under 19 years.
Highlights
Thyroid cancer, a relatively rare neoplasm, accounts for 213,000 new cases worldwide annually
A significant decrease was detected in the trend of thyroid cancer in children
According to the data recently released by the American National Cancer Institute (NCI), thyroid cancer increased at a rate of 6.5 percent per year from 1997 to 2006, emerging as the fastest increasing cancer among men and women (Kilfoy et al, 2009)
Summary
A relatively rare neoplasm, accounts for 213,000 new cases worldwide annually. 1–5% of the cases of this cancer occur in females and
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