Abstract
Background Patients with familial adenomatous polyposis (FAP) are perceived to be at increased risk for developing thyroid cancer. However, screening guidelines for thyroid cancer in FAP patients are not well established. To report the prevalence of thyroid cancer and benign thyroid disease in FAP patients in a single-center hereditary colorectal cancer registry. Methods A retrospective chart review of all FAP patients enrolled in the MKSCC Hereditary Colorectal Cancer Family Registry was performed.
Highlights
Patients with familial adenomatous polyposis (FAP) are perceived to be at increased risk for developing thyroid cancer
Four patients (6.1%) had a history of thyroid cancer (TC), and underwent thyroidectomy
The prevalence of thyroid cancer in our FAP population (6.1%) is increased relative to the general population, and is within the range of that reported by others (112%)
Summary
Thyroid cancer and benign thyroid disease in patients with familial adenomatous polyposis (FAP): Memorial Sloan-Kettering Cancer Center (MSKCC) registry experience. Arnold J Markowitz1*, Gerard Chang, Lisa Cortina, Erin E Salo-Mullen, Jose G Guillem. From 14th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer Dallas, TX, USA. From 14th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer Dallas, TX, USA. 12-13 October 2010
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