Abstract
In a previous work we pointed out the high correlation among the presence of antithyroid antibodies (AB), thyroid function alteration and clinical symptoms in children with insulin dependent diabetes mellitus (DMID). In the actual study, the chronic lymphocitic thyroiditis (CLT), antithyroid AC and alteration function in patients with DMID was evaluated. From a total of 228 pts, in 78 (age 11.6 + 4.3), basal TSH and/or post TRH, T4, T3 by RIE and microsomal antifraction (MiAF) antithyroid AC and antithyroglobulin (ATg) haemoglutination was done. CLT presence (Fisher's criteria) was determined in 20 pts (25%): 16 girls, 4 boys; 11,6 years + 3.43, 90% (18/20) of which presented thyroid function alteration with high basal TSH X 7.39 + 3.49 uUml (p of 25 uUml). 85% of the patients presented clinical symptoms; goiter was detected in 65%. CLT prevalence was significatively greater in the first four years of the diabetes evolution. The frequency of MiAF positive titles was 15.4% of the diabetic and 50% of CLT patients. Due to the high prevalence, 25%, we conclude that thyroid function study, AC dosage and clinical exam must be included in all the children with DMID, specially in the first four years after the onset of the disease.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
