Abstract

It was found that Pediococcus cerevisiae ATCC 8081 can grow and produce acid on μg amounts of instead of mμg amounts of folinic acid SF (citrovorum factor) to a considerably better extent with a thymidine enhancement factor.The factor present in some microbiological media was identified as an effect of Tween 80 present in the medium. Similar effect was obtained also by other non-toxic detergents and was considered to be surface tension lowering, since it was (a) unspecific for the chemical nature of the factor (b) of the all-or-none type (c) dependent on a defined water/liquid interfacial tension.The bearing of changes in surface tension of the environment causing selective nutritional effects was discussed.

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