Abstract
A 17-year-old male with chronic mucocutaneous candidiasis, Addison's disease, pernicious anaemia, and malabsorption complicated by multiple B-vitamin deficiencies was transplanted twice with fetal thymic tissue. Previously negative in-vitro blastogenic response to candida became positive within one week of the first transplant and was restored to normal by the second transplant. A positive candida skin test was seen for the first time in 4 years. The patient's clinical condition has improved and there has been clearing of oral candidal lesions and increased ability to mount a vigorous inflammatory response.
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