Abstract

BackgroundMicrosomal prostaglandin E synthase-1 (mPGES-1) catalyzes the terminal step in the biosynthesis of PGE2, a critical mediator in the pathophysiology of osteoarthritis (OA). Histone methylation plays an important role in...

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Similar Papers

Paper Title
Journal
Date
Author
Genetic association analysis of radiographic hip osteoarthritis with established loci for bone mineral density: data from the osteoarthritis initiative
L.M Yerges-Armstrong ... M.C Hochberg
Osteoarthritis and cartilage | VOL. 22
L.M Yerges-Armstrong, et. al.L.M Yerges-Armstrong ... M.C Hochberg
20 Mar 2014
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.
Fatima El Mansouri ... Hassan Fahmi
Arthritis research & therapy | VOL. 16
Fatima El Mansouri, et. al.Fatima El Mansouri ... Hassan Fahmi
01 Jan 2014
HDAC4 contributes to IL‐1‐induced mPGES‐1 expression in human synovial fibroblasts through up‐regulation of Egr‐1 transcriptional activity
Nadir Chabane ... Xinfang Li
Journal of Cellular Biochemistry | VOL. 106
Nadir Chabane, et. al.Nadir Chabane ... Xinfang Li
29 Dec 2009
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes
H Afif ... H Fahmi
Arthritis research & therapy | VOL. 6
H Afif, et. al.H Afif ... H Fahmi
01 Jan 2004
View more papers

More From: Annals of the Rheumatic Diseases

Paper Title
Journal
Date
Author
From fibrositis to fibromyalgia to nociplastic pain: how rheumatology helped get us here and where do we go from here?
Daniel J Clauw
Annals of the Rheumatic Diseases | VOL. -
Daniel J ClauwDaniel J Clauw
06 Aug 2024
Development of international consensus on a standardised image acquisition protocol for diagnostic evaluation of the sacroiliac joints by MRI: an ASAS–SPARTAN collaboration
Robert G W Lambert ... Walter P Maksymowych
Annals of the Rheumatic Diseases | VOL. -
Robert G W Lambert, et. al.Robert G W Lambert ... Walter P Maksymowych
06 Aug 2024
Journey through discovery of 75 years glucocorticoids: evolution of our knowledge of glucocorticoid receptor mechanisms in rheumatic diseases
Ann-Kathrin Eiers ... Jan P Tuckermann
Annals of the Rheumatic Diseases | VOL. -
Ann-Kathrin Eiers, et. al.Ann-Kathrin Eiers ... Jan P Tuckermann
06 Aug 2024
Helicobacter pylori upregulates PAD4 expression via stabilising HIF-1α to exacerbate rheumatoid arthritis
Hui Wu ... Chao Wu
Annals of the Rheumatic Diseases | VOL. -
Hui Wu, et. al.Hui Wu ... Chao Wu
06 Aug 2024
View more papers