THU0371 Increased expression of inflammatory cytokines and chemokines in an autoinflammatory disorder, nakajo-nishimura syndrome

Abstract

BackgroundThe ubiquitin-proteasome pathway is responsible for selective degradation of short-lived, misfolded and toxic proteins. It plays an important rule in transcriptional regulation.Nakajo-Nishimura syndrome (NNS) (MIM 256040) is an autosomal recessive...