THU0205 Targeting the Bone-Driven Phenotype of OA by A Novel Calcitonin Analogue, Kbp088, Affecting Both Bone and Cartilage Turnover as Well as Metabolic Health

Abstract

BackgroundOsteoarthritis (OA) may be segregated into different disease phenotypes based on disease drivers; cartilage damage, joint inflammation or subchondral bone remodelling. Each phenotype may require targeted treatments. Patients with a...