THU0034 The inflammatory potential of calcium pyrophosphate crystals depends on their capacity to induce nf-κb and mapk pathways

Abstract

BackgroundCalcium pyrophosphate (CPP) crystal-induced inflammation is mainly driven by interleukin (IL)-1β. IL-1β production involves a two-step process including the formation of pro-IL-1β through NF-κB activation and its maturation inti active...