Thrombotic Thrombocytopenic Purpura-like Illness in a Patient With Anti-Glomerular Basement Membrane Antibody Disease

Abstract

Anti-glomerular basement membrane (anti-GBM) disease or Goodpasture's disease is characterized by the presence of anti-GBM antibodies causing glomerulonephritis often in conjunction with diffuse alveolar hemorrhage. A small number of cases in the literature report anti-GBM disease presenting with thrombotic thrombocytopenic purpura (TTP)-like illness. We report an unusual case of anti-GBM disease with thrombocytopenia and microangiopathic hemolytic anemia (MAHA) in …