Abstract
A 70-year-old man who tested positive for SARS-CoV-2 presented to the hospital with confusion and a seizure. A computed tomography of the head was normal. The initial complete blood count showed severe thrombopenia and microangiopathic hemolytic anemia. Low ADAMTS13 activity confirmed the diagnosis of thrombotic thrombocytopenic purpura (TTP). Treatment with corticosteroids and plasma exchange was successful and the patient recovered completely. As no other causes were found, COVID-induced TTP was diagnosed. A combination of inflammation and immune dysregulation could explain this presentation.
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