Abstract

w c v t i e s -Aminocaproic acid (EACA) is used to treat bleeding associated with systemic brinolysis, as well as hematuria resulting rom urinary tract procedures or tumors. EACA nhibits urokinase and other activators of plasinogen, decreasing the formation of plasmin nd inhibiting the breakdown of fibrin. ACA-associated renal failure may be caused y obstruction of the upper urinary system by lood clots, hypotension with acute tubular ecrosis, renal infarction, and myoglobinuria. his is the first report of EACA causing renal ailure by accelerating a preexisting thromotic microangiopathic process.

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