Abstract
Thrombospondin-1 expresses in a variety of tumors and induces endothelial cell apoptosis,thus inhibits tumor angiogenesis and prevents tumor growth.It function domain ( Type I sequence):3TSR,retaines the function of inhibit angiogenesis,has the certain practical significance in clinical cancer treatment. Key words: Thrombospondin 1 ; Angiogenesis inhibitors; Apoptosis; Three thrombospondin-1 type 1 repeats
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