Thromboembolic complications in COVID-19 patients

Abstract

The infections caused by coronavirus-2 very often lead to severe, acute respiratory damages, because of which respiratory insufficiency is manifested. As a result, since the development of pneumonias (December, 2019), many patients have required hospitalization. When treating the severe pneumonia cases, it was proved that in a significant number of patients with respiratory inflammatory processes, venous, less often arterial thrombosis occured, making the clinical state even more severe. We treated 1590 coronavirus-2 infected, pneumonia-connected patients between September, 2020 and March, 2021 at our department. We examined the nature and the proportion of the thromboembolic complications. We determined the severity of pneumonia in the 1950 coronavirus-2 infected patients; when clinically suspected, they had lower limb Doppler ultrasound examination and angiography carried out with computer tomograph. The result of imaging examinations proved that in 13% of cases deep vein thrombosis occured; in 17% of cases acute pulmonary embolia occured with pneumonia caused by coronavirus-2. In coronavirus-2 infected cases, mainly in the lung, but also in other organs (heart, kidney, liver), severe inflammatory disease-processes may occur, as a result of which increased thrombosis tendency shows because of the ineraction of the inflammatory and coagulatory system. As a result of the increased thrombosis tendency, venous and less often arterial thrombosis worsen the clinical state of patients, and have unfavourable effect on life expectancy. Orv Hetil. 2021; 162(43): 1710-1716.