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Abstract
1.1. A study of the problem of specific hypersensitiveness of the skin to tobacco in 35 typical cases of thromboangiitis obliterans and 35 controls was made.2.2. The patients with thromboangiitis obliterans did not show a higher evidence of positive skin reactions than the control group.3.3. The high incidence of positive skin reactions to tobacco tests reported by other investigators and interpreted as allergic reactions is considered due to some of the many nonspecific reactions from chemical irritation.4.4. Thrombo-angiitis obliterans is not caused by an allergic type of tobacco hypersensitiveness.
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