Three-dimensional biomechanical properties of the human cervical spine in vitro

Abstract

Our aim was to determine the biomechanical properties of the normal human cervical spine under physiological static loads. The three-dimensional displacements under three pure moments: flexion-extension, left-right lateral bending and left-right axial torsion--were measured in 56 intact functional spinal units (FSUs) taken from between C2 and C7 in 29 human cadavers. For each mode of loading, load-displacement curves were plotted. Then we calculated each neutral zone, range of motion, neutral zone ratio, ratio of coupled motion, limit moment and secant stiffness. The effects of intervertebral disc degeneration and the disc level were also taken into account by the analysis of variance. Our results adequately demonstrated both the non-linearity of load-displacement curves and the neutral zone of the cervical spine in three-dimensional space. At the same time, we found statistically that the stiffness in the three planes are significantly different, as are the stiffnesses in lateral bending of successive different FSUs. However, significant differences of stiffness in different states of disc degeneration were only found in right lateral bending. There were significant differences between levels in ratio of coupled motion under both lateral bending and axial torsion. The loading cycle conditions and the biomechanical responses of principal motion of C1-2 are also reported.