Three-year durability of pain and disability improvements in patients treated with Restorative Neurostimulation for chronic mechanical low back pain

Abstract

Introduction: Mechanical chronic low back pain (CLBP) can be caused by impaired neuromuscular control and degeneration of the multifidus muscles, the most important stabilizers of the lumbar spine. An implantable Restorative Neurostimulation system (ReActiv8® by Mainstay Medical) bilaterally stimulates the medial branches of the L2 dorsal rami to override underlying multifidus inhibition to facilitate motor control restoration. The ReActiv8-B randomized sham-controlled pivotal trial provided published evidence of safety, effectiveness, and durability of this therapy (clinicaltrials.gov/show/NCT02577354).