Three rearranged 2(3→20) abeotaxanes from the bark of Taxus mairei

Abstract

Three new rearranged 2(3→20) abeotaxane diterpenoids were isolated from the bark of the Chinese yew, Taxus mairei. Their structures were established as 2α,5α,7β,13α-tetraacetoxy-10β-hydroxyl-2(3→20) abeotaxan-9-one; 7β,13α-diacetoxyl-2α,5α,10β-trihydroxyl-2(3→20) abeotaxan-9-one and 2α,7β-diacetoxy-5α,10β,13α-trihydroxyl-2(3→20) abeotaxane-9-one on the basis of 1D and 2D NMR data. This is the first example of rearranged 2(3→20) abeotaxanes were isolated from Taxus mairei.