Three New Sesquiterpene Pyridine Alkaloids from Euonymus fortunei

Abstract

AbstractThree new macrocyclic β‐dihydroagarofuran‐type sesquiterpene pyridine alkaloids, fortuneines A (1), B (2), and C (3), together with the four known alkaloids wilfornine E (4), aquifoliunine E‐I (5), euoverrine B (6), and euojaponine I (7), were isolated from the aerial parts of Euonymus fortunei. Their structures were elucidated by spectroscopic methods, including HR‐ESI‐MS, 1H‐ and 13C‐NMR, DEPT, 1H,1H‐COSY, HSQC, HMBC, and ROESY. This is the first isolation of the above sesquiterpene pyridine alkaloids from this plant, except for compound 6.