Three new flavonol glycosides from Suaeda maritima

Abstract

Three new flavonol glycosides isolated from the 70% methanol extract of Suaeda maritima (Chenopodiaceae) were characterized based on spectroscopic and chemical methods as quercetin 3-O-α-l-rhamnopyranosyl(1″′ → 6″)-β-d-galactopyranoside-7-O-β-d-glucopyranosyl(1″″′ → 2″″)-glucopyranoside, kaempferol 3-O-α-l-rhamnopyranosyl(1″′ → 6″)-β-d-galactopyranoside-7-O-β-d-glucopyranosyl(1″″′ → 2″″)-glucopyranoside, and kaempferol 3-O-α-l-rhamnopyranosyl(1″′ → 6″)-β-d-galactopyranoside-7-O-(2″″′-O-trans-feruloyl)-β-d-glucopyranosyl-(1″″′ → 2″″)-β-d-glucopyranoside. In addition, four known compounds, namely, quercetin and kaempferol, methyl cis, trans-ferulate, and methyl trans-ferulate were identified. The plant extract and these compounds showed cytotoxic activity against the human tumor cell lines MCF7, HCT116, and HEPG2.