Three New 2(3→20)-Abeo-Taxoids from the Bark of the Chinese Yew, Taxus mairei

Abstract

Three new rearranged 2(3→20)abeo-taxane diterpenoids with the unique 6/10/6 skeletons were isolated from the bark of the Chinese yew, Taxus mairei. Their structures were established as 2α, 10β, 13α-triacetoxy-2(3→20)-abeo-taxa-4(20),5,11-triene-7,9-diones, 2α,13α-diacetoxy-10β-hydroxy-2(3→20)-abeo-taxa-4(20),5,11-triene-7,9-diones, and 2α,5α,13α-triacetoxy-7β,10β-dihydroxy-2(3→20)abeo-taxa-4(20),11-diene-9-one on the basis of 1D and 2D NMR data.