Abstract

This article presents a method for measuring three-dimensional mechanicaldisplacement and strain fields using stimulated echo MRI. Additional gradientpulses encode internal displacements in response to an externally applieddeformation. By limiting the mechanical transition to the stimulated echomixing time, a more accurate static displacement measurement is obtained. Athree-dimensional elasticity reconstruction within a region of interest havinga uniform shear modulus along its boundary is performed by numerically solvingdiscretized elasticity equilibrium equations. Data acquisition, strainmeasurements and reconstruction were performed using a silicone gel phantomcontaining an inclusion of known elastic properties. A comparison betweentwo-dimensional and three-dimensional reconstructions from simulated andexperimental displacement data shows higher accuracy from thethree-dimensional reconstruction. The long-term objective of this work is toprovide a method for remotely palpating and elastically quantitating manuallyinaccessible tissues.

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