Three-dimensional reconstruction of the "bright ring" echogenicity from porcine blood upstream in a stenosed tube

Abstract

To investigate the echogenicity variation due to blood flow disturbance near a stenosis under pulsatile flow, a series of in vitro experiments were performed in a rigid tube with an eccentric stenosis of 70% area reduction in a mock flow loop. An ultrasonic B-mode with a Doppler spectrogram was used to correlate echogenicity with flow speed and stroke rate. This paper reports echogenicity variation upstream of a stenosis under pulsatile flow. The experimental results showed that blood flow disturbed by the stenosis affects echogenicity and red blood cell rouleaux upstream. A hypoechoic "black hole" was shown at the center of the stream at systole. During diastole, the "bright ring" in cross-sectional images was observed as eddy-like or parabolic profiles in longitudinal images. These images could be reconstructed into a 3-dimensional animation, providing a better understanding of dynamic changes of the rouleaux distribution upstream of a stenosis under pulsatile flow.