Abstract

Dopamine (DA) neurotransmitter is a prominent component of the central nervous system and its deficiency contributes to several diseases, such as Parkinson’s disease and schizophrenia, which significantly influence the quality of life of affected individuals. This paper introduces a circular interdigitated ring electrode, the three-dimensional carbon interdigitated ring array nanofibers (3D C-IDRA NFs), for the detection of DA using amperometric detection. The study utilized cyclic voltammetry and chronoamperometry to investigate DA. The integration of carbon nanofibers (CNFs) with 3D C-IDRA demonstrated enhanced surface area, increased current peak, and superior performance compared to the standalone 3D C-IDRA electrode, as evidenced by a redox amplification factor of 2.94 and a collection efficiency of 81.1%. The results highlight that integrating CNFs with 3D C-IDRA improves the electrochemical performance in detecting DA neurotransmitter. Thus, this discovery elucidates the advantageous potential of the 3D C-IDRA NF electrode in a wide range of applications.

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