Abstract
AbstractAn eco‐friendly and highly efficient process has been applied to synthesize spirooxindole‐pyran derivatives in a one‐pot container via a three‐component reaction of isatins, malononitrile, and an enolizable CH‐activated compound of diethyl 3‐oxopentanedioate under constant current in n‐propanol under a temperature of 50°C. The proposed method shows high yields through green reaction conditions along with other significant advantages. Among which stand out applying clean electrons as a reproducible source of energy instead of an organic catalyst, using an environmentally friendly solvent for instance propanol, a multicomponent reaction with mild condition happening in a one‐pot container, and no chromatographic separation.
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