Abstract
A synergistic Rh(II)/Pd(0) dual-catalyzed strategy that enabled three-component oxy-allylation of α-diazo esters, alcohols, and allylic benzoates was described. Trapping of active protic oxonium ylides with catalytic π-allyl Pd(II) intermediates was proposed for this reaction. More strikingly, water was also a suitable partner in this reaction involving a different allylic migratory insertion of palladium-carbenes. These transformations provided straightforward access to various α-ternary allylated carboxylic esters using simple and readily available starting materials under redox-neutral conditions, in which two new CO and CC bonds were generated successively at the carbene center.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
