Abstract

SUMMARYDisseminated intravascular coagulation (DIC) was a complication in 3 patients with different primary diseases. The probable initiation of the DIC was a thromboplastic active tumor, a laceration wound at cesarean section with amniotic embolism in the foetus and probable endotoxin release in a newly kidney biopsied patient with subacute glomerulonephritis. The DIC was interrupted in the first patient by extirpation of the tumor, in the other two by treatment with heparin in spite of bleeding tendency.The diagnosis can be strongly suspected by demonstrating a decrease of the fibrinogen content combined with a diminished number of platelets. A normalization of the condition can occur after interruption of the intravascular clotting by treatment with heparin.

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