Abstract
We encountered three cases of bilateral Acanthamoeba keratitis and reviewed six cases of bilateral Acanthamoeba keratitis including our three cases in Japan. 1. A 40-year-old woman had worn soft contact lenses (SCLs) and her visual prognosis was good because the lesion was at an initial stage in each eye. 2. A 35-year-old woman had worn hydrophobic SCLs, and needed bilateral superficial keratectomy, because the lesion was at a transient stage in each eye and her visual prognosis was poor. 3. A 37-year-old woman had worn hydrophobic SCLs and her visual prognosis was good because the lesion was at an initial stage in each eye. The condition was observed only in SCL and hydrophobic SCL wearers. All SCL wearers were cured easily and their visual prognosis was good, but in hydrophobic SCL wearers, two cases out of three, visual prognosis was poor. Bilateral Acanthamoeba keratitis has been so far observed only in SCL or hydrophobic SCL wearers. Hydrophobic SCL wearers tend to have poor visual prognosis.
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