Abstract
C-H Bond Activation It's rather straightforward to oxidize hydrocarbons indiscriminately—that's the type of reaction that supplies heat to gas-powered stoves and furnaces. Chemists interested in making pharmaceuticals or consumer products do not want to end up with just carbon dioxide and water though. Instead, they want to transform certain specific C-H bonds without disturbing the rest of the molecule. Paradine et al. report a manganese catalyst that slides pendant N into C-H bonds with high tolerance for otherwise-reactive C=C double bonds nearby. At the same time, the catalyst shows surprisingly high reactivity toward very strong C-H bonds (including primary alkyl sites) that previous selective catalysts failed to engage. Nat. Chem. 10.1038/NCHEM.2366 (2015).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
