Abstract

Lactoperoxidase, a prototypical mammalian peroxidase, is part of an antimicrobial system found in secreted fluids.1 It is believed to act by oxidation of thiocyanate.2 Not surprisingly, it will also metabolize thiol moieties, oxidizing them to free radical intermediates. Thiol compounds are important in pharmacology and toxicology, and we have examined the production of highly reactive thiyl free radicals by this mechanism.KeywordsAmes TestNorth Carolina 27514Thiol CompoundInstrumental ConditionThiyl RadicalThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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