Abstract
Colorectal cancer is major cause of mortality and morbidity, but early detection of precancerous polyps or low-grade malignant lesions leads to high rates of survival. In present clinical practice, screening for cancer and polyps is based on clinical risk evaluation, fecal occult blood testing, and flexible sigmoidoscopy or colonoscopy. However, owing to the low sensitivity of fecal occult blood testing and the perceived invasive nature of endoscopic procedures, these screening methods are far from optimal.
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