Abstract

To investigate the prevalence of suicidal thoughts and behaviours (STB; i.e. suicidal ideation, plans or attempts) in the Spanish adult general population during the first wave of the Spain coronavirus disease 2019 (COVID-19) pandemic (March-July, 2020), and to investigate the individual- and population-level impact of relevant distal and proximal STB risk factor domains. Cross-sectional study design using data from the baseline assessment of an observational cohort study (MIND/COVID project). A nationally representative sample of 3500 non-institutionalised Spanish adults (51.5% female; mean age = 49.6 [s.d. = 17.0]) was taken using dual-frame random digit dialing, stratified for age, sex and geographical area. Professional interviewers carried out computer-assisted telephone interviews (1-30 June 2020). Thirty-day STB was assessed using modified items from the Columbia Suicide Severity Rating Scale. Distal (i.e. pre-pandemic) risk factors included sociodemographic variables, number of physical health conditions and pre-pandemic lifetime mental disorders; proximal (i.e. pandemic) risk factors included current mental disorders and a range of adverse events-experiences related to the pandemic. Logistic regression was used to investigate individual-level associations (odds ratios [OR]) and population-level associations (population attributable risk proportions [PARP]) between risk factors and 30-day STB. All data were weighted using post-stratification survey weights. Estimated prevalence of 30-day STB was 4.5% (1.8% active suicidal ideation; n = 5 [0.1%] suicide attempts). STB was 9.7% among the 34.3% of respondents with pre-pandemic lifetime mental disorders, and 1.8% among the 65.7% without any pre-pandemic lifetime mental disorder. Factors significantly associated with STB were pre-pandemic lifetime mental disorders (total PARP = 49.1%) and current mental disorders (total PARP = 58.4%), i.e. major depressive disorder (OR = 6.0; PARP = 39.2%), generalised anxiety disorder (OR = 5.6; PARP = 36.3%), post-traumatic stress disorder (OR = 4.6; PARP = 26.6%), panic attacks (OR = 6.7; PARP = 36.6%) and alcohol/substance use disorder (OR = 3.3; PARP = 5.9%). Pandemic-related adverse events-experiences associated with STB were lack of social support, interpersonal stress, stress about personal health and about the health of loved ones (PARPs 32.7-42.6%%), and having loved ones infected with COVID-19 (OR = 1.7; PARP = 18.8%). Up to 74.1% of STB is potentially attributable to the joint effects of mental disorders and adverse events-experiences related to the pandemic. STB at the end of the first wave of the Spain COVID-19 pandemic was high, and large proportions of STB are potentially attributable to mental disorders and adverse events-experiences related to the pandemic, including health-related stress, lack of social support and interpersonal stress. There is an urgent need to allocate resources to increase access to adequate mental healthcare, even in times of healthcare system overload. NCT04556565.

Highlights

  • The coronavirus disease 2019 (COVID-19) pandemic poses unprecedented challenges worldwide

  • In this report we investigate 30-day suicidal thoughts and behaviours (STB) during the first wave of the COVID-19 pandemic (March−June 2020) in the Spanish adult general population

  • STB estimates stratified by distal risk factors and current mental disorders are shown in online Supplementary Table 4

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Summary

Introduction

The coronavirus disease 2019 (COVID-19) pandemic poses unprecedented challenges worldwide. Research is needed to provide reliable STB prevalence estimates and to quantify the population-level impact of relevant risk factors (Christensen et al, 2016). The latter can be achieved by calculating population attributable risk proportions (PARP; Krysinska and Martin 2009), i.e. estimates of potential reductions in STB when eliminating risk factors in the population. No previous data exist on STB prevalence during the pandemic in Spain other than from an online survey (March 2020) based on non-representative snowball sampling (Sáiz et al, 2020). Proximal risk factors (i.e. referring to the pandemic period) are current mental disorders (Fitzpatrick et al, 2020; Iob et al, 2020); health-related factors, including COVID-19 infection (Iob et al, 2020; Winkler et al, 2020) and health-related stress (Winkler et al, 2020; Ammerman et al, 2021); financial factors (Fazel and Runeson, 2020), including COVID-19-related financial stress or job loss (Gratz et al, 2020; Winkler et al, 2020); and interpersonal factors, including interpersonal stress and lack of social support (O’Connor and Kirtley, 2018; Carrasco-Barrios et al, 2020)

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