Abstract

A rare systemic inflammatory disorder is Adult onset Still's disease (AOSD), characterized by diverse clinical and laboratory findings, which is often difficult to diagnose. It is responsible for a significant proportion of cases of acute febrile illness in young adults. Adult Onset Stills Disease (AOSD) usually affects multiple organs, but it is a diagnosis of exclusion. Here we describe a case of a 32-year old patient with fever of unknown etiology, arthralgia, sore throat and skin rash. The final diagnosis of Still's disease was made by clinical and laboratory criteria and exclusion of other causes of similar presentation. Â DOI = 10.3329/jom.v9i1.1428 J MEDICINE 2008; 9 : 58-61

Highlights

  • Adult onset Still’s disease (AOSD) is a rare systemic inflammatory disorder the aetiology of which is unknown, and the quotidian or double-quotidian spiking fevers with an evanescent rash, arthritis, and multiorgan involvement are the characteristic feature

  • In 1897 George Still published his monograph, in which he describes 22 children with signs and symptoms of the disease entity currently known as systemic onset juvenile idiopathic arthritis

  • In 1896 the Lancet first published the description of an adult patient with signs and symptoms of AOSD, which is labeled as rheumatoid arthritis

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Summary

Introduction

Adult onset Still’s disease (AOSD) is a rare systemic inflammatory disorder the aetiology of which is unknown, and the quotidian or double-quotidian spiking fevers with an evanescent rash, arthritis, and multiorgan involvement are the characteristic feature. The Case Report: A 32 year old man hailing from Badda Dhaka, presented to us, at Medicine Out Patient Department, DMCH with 6 weeks history of high fever with rigors and spikes at night lasts for 4-5 hours and relived with sweating. He had pain in joints involving both knee, shoulder, elbow and metacarpophalangeal joints and erythematous rash all over the trunk. On examination he was found to be febrile with Temperature: 39°C, non-itching macular erythematous rash on the trunk.

Discussion
Findings
Negative RA and DNA
Conclusions
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