Abstract
Third Molar Coronectomy in a Patient with Florid Osseous Dysplasia: A New Application for a known Technique
Highlights
Biological Activity of Coumarin Derivates and their Lanthanoid ComplexesCoumarin (2H-1-benzopyran-2-one) and its derivates are large class of chemical compounds, most of them naturally occurring and can be found in plants [1], fungi and bacteria [2,3] or can be synthesized with a modification of the coumarin ring [4,5,6]
A suggestion has been made that the antibacterial activity depends on the position of substituents and the 3,3’-(4-hydroxybenzylidene)-bis-4-hydroxycoumarin skeleton is essential for the activity [18]
Their complexes with different metal ions have been found to possess antimicrobial activity i.e. the implementing of a metal ion in the structure of the coumarin can lead to enhancing its biological activity [21,22,23]
Summary
Biological Activity of Coumarin Derivates and their Lanthanoid ComplexesCoumarin (2H-1-benzopyran-2-one) and its derivates are large class of chemical compounds, most of them naturally occurring and can be found in plants [1], fungi and bacteria [2,3] or can be synthesized with a modification of the coumarin ring [4,5,6]. Due to the different types of substitution of the parent ring, coumarins are extremely variable in structure resulting in variety of their properties Both natural and synthetic coumarins are reported to have properties such as antioxidant [7,8], antifungal [9,10], antitumor [11,12,13], anti-HIV [14,15], anticoagulant [16,17], antibacterial [18,19,20], etc. A suggestion has been made that the antibacterial activity depends on the position of substituents and the 3,3’-(4-hydroxybenzylidene)-bis-4-hydroxycoumarin skeleton is essential for the activity [18] Besides the coumarins, their complexes with different metal ions have been found to possess antimicrobial activity i.e. the implementing of a metal ion in the structure of the coumarin can lead to enhancing its biological activity [21,22,23]. Complexes of lanthanoids with various coumarin compounds have been synthesized and screened for their biological activity [24,25,26,27,28,29]
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