Abstract
Thiopeptin, an acidosis-preventive antibiotic, was fed with a high-concentrate rolled corn diet in a factorial experiment with two roughage levels (15 and 5% cottonseed hulls) and two diet adaptation schemes to 111 growing steers. Thiopeptin supplementation at 11 ppm increased rate of gain by 5.3% (P<.10) and feed efficiency by 7.8% (P<.01) over the 129-day trial. Carcass characteristics remained unaffected. The higher roughage level increased feed intake (8.7%), but decreased feed efficiency (6.8%) indicating that the added hulls were poorly utilized. Incidence and severity of liver abscesses tended to be lower with the higher roughage level and the more rapid diet adjustment scheme.
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